Management of Widespread Laryngeal Papillomatosis

Clinical course of laryngeal papillomatosis

Laryngeal papillomatosis (LP) can have various clinical courses. Malignant transformation is rare. The purpose of the present study was to correlate the clinical course of the disease with the histopathologic findings of the surgically removed papillomas. In the series of 123 patients, abnormal or atypical epithelial hyperplasia of the papillomas removed at the first surgical procedure appeared...

Electron Microscopic Study of Human Laryngeal Papillomatosis.

Sixteen biopsies of laryngeal papillomas from patients 4-21 years old, as well as tissue from scarred areas of laryngeal mucosa which previously bore papillomas, were studied with the electron microscope and compared with normal laryngeal mucosa. Tissue blocks that contained cytoplasmic bodies by light microscopy were serially sectioned for electron microscopic examination. The bodies appeared ...

[Oral blastomycosis, laryngeal papillomatosis and esophageal tuberculosis].

Esophageal involvement is an extremely rare complication of tuberculosis even in countries with high prevalence of infection. We report the case of a 57 year-old hiv-seronegative patient with simultaneous diagnoses of oral blastomycosis and laryngeal papillomatosis. Both were confirmed by anatomopathological analysis. The esophageal biopsy revealed granulomatous esophagitis with necrosis and zi...

Cidofovir injection for recurrent laryngeal papillomatosis.

BACKGROUND Recurrent laryngeal papillomatosis is caused by the human papilloma virus and characterized by multiple exophytic lesions of the vocal tract; it is a benign disease, but one that tends to recur after removal of growths. Due to the nature of the disease, alternative treatment strategies have focused on antiviral injection at lesion sites that eliminate repeated surgical procedures. Th...

Laryngeal papillomatosis in an AIDS patient.